Cell culture and motility study on a polymer surface with a nanometer-scaled stripe structure.
نویسندگان
چکیده
We developed a large cell culture surface with a nanostripe structure by paving polydimethylsiloxane (PDMS) replicas of a glass mold. The stripe structure has a height of 180 nm and top width of 500 nm with 400-nm intervals between stripes. Human stomach cancer SH-10-TC cells cultured on the surface changed their morphology to elongated shapes parallel to the nanostripes. In addition, cell motility parallel to the stripes was greatly enhanced. These findings strongly suggest that the nanostripe structure affected the cell physiology.
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عنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 74 3 شماره
صفحات -
تاریخ انتشار 2010